So there was a Blue post on Monday indicating more changes to the epic gem transmutes that were just discovered last week. Most importantly to all Alchemists is the addition of a cooldown:
If you click on the image, you can clearly see in my chat log where I transmuted an Eye of Zul. And here on the Cardinal Ruby recipe the 20 hour cooldown is in effect. This cooldown appears to be shared between all of the epic gems. I checked each of them and they all had the same timer. For those of you wondering (hoping) whether the CD would stay off, at this point it time it looks like that's not going to happen.
The other major change is that the mats have been completely redone for all of the epic gem recipes:
I have to say that these new mats certainly make more sense than the old ones. Except the Eye of Zul... 3x Eternal Life... what's that about? Blizz is determined to keep Forest Emeralds useless. Aside from that oddity, it's fairly logical that you'd combine a rare gem and an eternal to create an epic version of the same color. That said, I'm pretty sad to see 3x Eye of Zul for a Cardinal Ruby going down the drain. I'm sure that's why they made the change though, folks were already stocking up on cheap rares to convert into the nicer epics. Now we'll have to use a valuable Ruby to get a valuable Ruby.
I think the real lesson here is, things can change on the PTR. Things can change radically on the PTR. Be wary of stocking items based on information coming out of the PTR.